AN EVALUATION OF PHYSICOCHEMICAL PARAMETERS AND QUANTITATIVE PHYTOCHEMICAL ANALYSIS OF DATURA METEL- A RESEARCH ARTICLE

Abstract [English]

Datura is known as a medicinal plant and plant hallucinogen all over the world. Datura is a rich source of alkaloids such as Hyoscyamine, hyoscine, scopolamine, atropine, with anolides (lactones) and other tropanes. Based on the presence of alkaloids, formulations containing Datura exhibit antibacterial, antioxidant, herbicidal, antifungal, antiviral and antiulcer properties. Historically, Datura has been employed in the treatment of skin disorders, ear pain, cough, fever, and asthma, among other traditional uses. Qualitative phytochemical test indicates the identification of primary metabolites (Carbohydrate, protein, fat etc.) and secondary metabolites (alkaloids, glycosides tannin etc.). Aim- Physicochemical parameters and quantitative phytochemical analysis of Datura metel. Material & Method- The powdered form of Datura seeds was prepared, and its physicochemical or phytochemical testing & standardization were conducted in accordance with established protocols. Results- Datura was evaluated for different standardization parameters which showed Loss on drying (7.36%), Total ash (7.26%), Acid insoluble ash (3.65%), Water soluble extractive (17.65%), Alcohol soluble extractive (12.25%) and Water-soluble ash (5.19%). Molisch test was positive in aqueous extract. Benedict test was positive in alcoholic extract. Fehling test was positive in aqueous extract. Alkaloids were identified in aqueous extract due to positive of Dragondroff test, Wagner’s test, and Hager’s test positive in aqueous extract. Amino acid was present in aqueous extract due to show positive result in Ninhydrine test. Proteins were present in test sample due to positive in Biuret test and Xenthoprotic test in aqueous extract. Foam test was positive in aqueous extract. Borntroger’s test positive in aqueous extract. Phenolic test was positive in aqueous and alcoholic extract. FeCl3 test, Pot. Dichromate test was positive in extract of seeds that’s indicate that tannin is present in sample. Conclusion- This paper highlights organoleptic characters and constituents of Datura metel and the data obtained from this study can be utilized to establish standards for Datura metel.