Journal of Ayurvedic Herbal and Integrative Medicine

PHYTOCHEMICAL PROFILING OF TINOSPORA CORDIFOLIA FOR THERAPEUTIC APPLICATIONS

Ragini Sikarwar — 2025-11-06

Tinospora cordifolia (commonly known as Guduchi or Giloy) is a medicinal climbing shrub widely used in traditional medicine for its immunomodulatory, hepatoprotective, and antidiabetic effects. The therapeutic potential of the plant is linked to its rich secondary metabolites, particularly alkaloids, glycosides, steroids, and phenolics. In the present study, chemical profiling of T. cordifolia stem extracts was performed to establish a comprehensive phytochemical fingerprint. Qualitative and quantitative assays confirmed the presence of diverse bioactive compounds, while chromatographic techniques highlighted key chemical markers such as berberine, tinosporaside, and cordifolioside. The results validate the pharmacological relevance of T. cordifolia and emphasize the importance of standardized phytochemical profiling for ensuring efficacy and safety of herbal formulations. This study provides a baseline for further pharmacological investigations and supports the integration of T. cordifolia into evidence-based herbal therapeutics.

CHEMICAL FINGERPRINTING OF ROOT EXTRACTS FROM WITHANIA SOMNIFERA

Ragini Sikarwar — 2025-10-15

Withania somnifera (Ashwagandha) is a medicinal plant of high therapeutic value, traditionally used in Ayurveda for stress management, immune modulation, and neuroprotection. Its pharmacological potential is largely attributed to diverse phytochemicals, particularly withanolides, alkaloids, and phenolic compounds. In the present study, root extracts of W. somnifera were subjected to chemical fingerprinting using advanced analytical techniques to establish a comprehensive phytochemical profile. Standardized chromatographic and spectroscopic methods were employed to identify key bioactive constituents and to generate reproducible chemical patterns. The results revealed the presence of characteristic secondary metabolites that can serve as quality markers for authentication and standardization. This study highlights the importance of fingerprinting approaches in ensuring consistency, efficacy, and safety of herbal preparations derived from W. somnifera. The findings also provide a foundation for future pharmacological investigations and the development of standardized formulations.

EXPLORING THE THERAPEUTIC POTENTIAL OF TRADITIONAL INDIAN DIETS IN MANAGING CHRONIC DISEASES

Sangeeta Ahirwar — 2025-11-17

Traditional Indian diets, deeply rooted in Ayurvedic and cultural practices, have gained renewed scientific attention for their role in preventing and managing chronic diseases. These diets emphasize plant-based foods, diverse grains, pulses, fermented foods, spices, and healthy fats—collectively offering a balance of macronutrients, micronutrients, and bioactive phytochemicals. This study explores the therapeutic potential of traditional Indian dietary patterns in mitigating chronic metabolic disorders such as type 2 diabetes, cardiovascular disease, obesity, and inflammatory conditions.

A hypothetical comparative model was constructed using literature-based data to analyze the nutrient composition and preventive efficacy of three dietary patterns: a Traditional Indian diet, a Western diet, and a Mediterranean diet. Parameters such as glycemic load, antioxidant content, and inflammatory markers were compared. The findings suggest that the Traditional Indian diet demonstrates superior outcomes in reducing oxidative stress (by ~30%) and systemic inflammation (by ~25%), while maintaining favorable lipid and glucose profiles.

The results underscore that traditional Indian dietary practices—characterized by whole grains (millets, brown rice), pulses, fermented dairy, and functional spices (turmeric, cumin, fenugreek)—offer a holistic, food-based therapeutic approach. These findings reinforce the value of cultural dietary wisdom when integrated with modern nutritional science, supporting chronic disease prevention through sustainable, regionally adapted nutrition strategies.