LYOPHILIZATION: AN IMPORTANT FORMULATION TECHNIQUE
DOI:
https://doi.org/10.29121/granthaalayah.v7.i9.2019.552Keywords:
Lyophilization, Formulation, TechniqueAbstract [English]
Lyophilization, is an important development for medicament formulation because of its ability to safely dry heat-sensitive vaccines, antibiotics, and protein-based formulations. The lyophilization process results in long shelf lives powder formulation which can be reconstituted at the point of use. As Injectable biopharmaceuticals become a more prominent part of the overall drug market the value of lyophilized product is has increased significantly. In 1998, lyophilized pharmaceuticals accounted for 11.9% of all new Injectable or infusible drugs, but, by 2015, they made up half of all such new drug introductions (Ratti et al 2001, Bubnovich et al 2012).
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