HOMOEOPATHIC MANAGEMENT OF TARGETED HAEMARTHROSES IN INHIBITOR POSITIVE HAEMOPHILIAC: A CASE REPORT
DOI:
https://doi.org/10.29121/granthaalayah.v11.i12.2023.5422Keywords:
Homoeopathy, Hemophilia, Target Joint, Inhibitor, HemarthrosesAbstract [English]
Haemarthroses is common presentation in haemophilia patient. Due to recurrent use of clotting factor concentrates for treatment and prophylaxis, of which about 20 % of patients produce antibodies to factor VIII and factor IX. This results in development of inhibitors in such patients which complicates the case even more. Homoeopathy the alternative form of treatment can be used in such case. This case report presents the management of haemarthroses in a haemophilia inhibitor. Well selected homoeopathic similimum helped in reversing the haemophilic arthropathy in left knee joint of the patient and even controlled the recurrence of the haemarthroses in target joint. The result was assessed using Hemophilia joint health assessment scale (HJHS). The result of before and after treatment was extremely significant with a p value of 0.0009 The individual curative response of the case was assessed using Modified naranjo criteria for homoeopathic case reporting, casual attribution (MONARCH).
Downloads
References
Buzzard, B. M., & Jones, P. M. (1988). Physiotherapy Management of Haemophilia: An Update. Physiotherapy, 74(5), 221-226. https://doi.org/10.1016/S0031-9406(10)63535-3 DOI: https://doi.org/10.1016/S0031-9406(10)63535-3
Buzzard, B., & Beeton, K. (2008). Physiotherapy Management of Haemophilia. John Wiley & Sons.
Hermans, C., De Moerloose, P., Fischer, K., Holstein, K., Klamroth, R., Lambert, T., Lavigne-Lissalde, G., Perez, R., Richards, M., Dolan, G. & European Haemophilia Therapy Standardisation Board. (2011). Management of Acute Haemarthrosis in Haemophilia a Without Inhibitors: Literature Review, European Survey and Recommendations. Haemophilia, 17(3), 383-392. https://doi.org/10.1111/j.1365-2516.2010.02449.x DOI: https://doi.org/10.1111/j.1365-2516.2010.02449.x
Lafeber, F. P. J. G., Miossec, P., & Valentino, L. A. (2008). Physiopathology of Haemophilic Arthropathy. Haemophilia, 14, 3-9. https://doi.org/10.1111/j.1365-2516.2008.01732.x DOI: https://doi.org/10.1111/j.1365-2516.2008.01732.x
Lamba, C. D., Gupta, V. K., van Haselen, R., Rutten, L., Mahajan, N., Molla, A. M., & Singhal, R. (2020). Evaluation of the Modified Naranjo Criteria for Assessing Causal Attribution of Clinical Outcome to Homeopathic Intervention as Presented in Case Reports. Homeopathy, 109(04), 191-197. https://doi.org/10.1055/s-0040-1701251 DOI: https://doi.org/10.1055/s-0040-1701251
Minno, M. D., Minno, G. D., Capua, M. D., Cerbone, A. M., & Coppola, A. (2010). Cost of Care of Haemophilia with Inhibitors. Haemophilia, 16(1), e190-e201. https://doi.org/10.1111/j.1365-2516.2009.02100.x DOI: https://doi.org/10.1111/j.1365-2516.2009.02100.x
Morfini, M., Haya, S., Tagariello, G., Pollmann, H., Quintana, M., Siegmund, B., Stieltjes, N., & Tusell, J. (2007). European study on orthopaedic status of haemophilia patients with inhibitors. Haemophilia, 13(5), 606-612. https://doi.org/10.1111/j.1365-2516.2007.01518.x DOI: https://doi.org/10.1111/j.1365-2516.2007.01518.x
Nilsson, I. M., Berntorp, E., Löfqvist, T., & Pettersson, H. (1992). Twenty-five Years' Experience of Prophylactic Treatment in Severe Haemophilia A and B. Journal of Internal Medicine, 232(1), 25-32. https://doi.org/10.1111/j.1365-2796.1992.tb00546.x DOI: https://doi.org/10.1111/j.1365-2796.1992.tb00546.x
Rodriguez-Merchan, E. C., Wiedel, J. D., Wallny, T., Hvid, I., Berntorp, E., Rivard, G. E., Goddard, J., Querol, F., & Caviglia, H. (2003). Elective Orthopaedic Surgery for Inhibitor Patients. Haemophilia, 9(5), 625-631. https://doi.org/10.1046/j.1365-2516.2003.00803.x DOI: https://doi.org/10.1046/j.1365-2516.2003.00803.x
Rodriguez-Merchan, E., Jimenez-Yuste, V., Aznar, J. A., Hedner, U., Knobe, K., Lee, C. A., Ljung, R., Querol, F., Santagostino, E., Valentino, L. A. & Caffarini, A. (2011). Joint protection in haemophilia. Haemophilia, 17, 1-23. https://doi.org/10.1111/j.1365-2516.2011.02615.x DOI: https://doi.org/10.1111/j.1365-2516.2011.02615.x
Rodríguez-Merchán, E. C. (2019). The Role of Orthopaedic Surgery in Haemophilia: Current Rationale, Indications and Results. EFORT Open Reviews, 4(5), 165-173. https://doi.org/10.1302/2058-5241.4.180090 DOI: https://doi.org/10.1302/2058-5241.4.180090
Roosendaal, G., Jansen, N. W. D., Schutgens, R., & Lafeber, F. P. J. G. (2008). Haemophilic Arthropathy: the Importance of the Earliest Haemarthroses and Consequences for Treatment. Haemophilia, 14, 4-10. https://doi.org/10.1111/j.1365-2516.2008.01882.x DOI: https://doi.org/10.1111/j.1365-2516.2008.01882.x
St-Louis, J., Abad, A., Funk, S., Tilak, M., Classey, S., Zourikian, N., McLaughlin, P., Lobet, S., Hernandez, G., Akins, S., Wells, A. J., Manco-Johnson, M., John, J., Austin, S., Chowdary, P., Hermans, C., Nugent, D., Bakeer, N., Mangles, S., Hilliard, P., Blanchette, V.S., Feldman, B. M., & Feldman, B. M. (2022). The hemophilia joint health score version 2.1 validation in adult patients study: a multicenter international study. Research and practice in thrombosis and haemostasis, 6(2). https://doi.org/10.1002/rth2.12690 DOI: https://doi.org/10.1002/rth2.12690
Valentino, L. A., Hakobyan, N., Enockson, C., Simpson, M. L., Kakodkar, N. C., Cong, L., & Song, X. (2012). Exploring the Biological Basis of Haemophilic Joint Disease: Experimental Studies. Haemophilia, 18(3), 310-318. https://doi.org/10.1111/j.1365-2516.2011.02669.x DOI: https://doi.org/10.1111/j.1365-2516.2011.02669.x
Van Haselen, R. A. (2016). Homeopathic Clinical Case Reports: Development of a Supplement (HOM-CASE) to the CARE Clinical Case Reporting Guideline. Complementary Therapies in Medicine, 25, 78-85. https://doi.org/10.1016/j.ctim.2015.12.019 DOI: https://doi.org/10.1016/j.ctim.2015.12.019
Wight, J., & Paisley, S. (2003). The Epidemiology of Inhibitors in Haemophilia A: A Systematic Review. Haemophilia, 9(4), 418-435. https://doi.org/10.1046/j.1365-2516.2003.00780.x DOI: https://doi.org/10.1046/j.1365-2516.2003.00780.x
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Omkar Kumat, Dr. Tapas Kundu, Gulfisha Mirza, Rita Kundu
This work is licensed under a Creative Commons Attribution 4.0 International License.
With the licence CC-BY, authors retain the copyright, allowing anyone to download, reuse, re-print, modify, distribute, and/or copy their contribution. The work must be properly attributed to its author.
It is not necessary to ask for further permission from the author or journal board.
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.