ORAL HEALTH PROTECTION THROUGH AN AYURVEDA POLY HERBAL FORMULATION- AN IN VITRO STUDY

Saranya Nadesakanthan; Asanka Sanjeewa; Inoka Uluwaduge; Priyani Peiris; Fahara Meedin; Samantha Bandara

doi:10.29121/jahim.v3.i1.2023.26

Authors

Saranya Nadesakanthan Graduate, B. Sc. Honours, Medical Laboratory Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Sri Lanka
Asanka Sanjeewa Graduate, B. Sc. Honours, Medical Laboratory Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Sri Lanka
Inoka Uluwaduge Professor, Department of Basic Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Sri Lanka
Priyani Peiris Professor, Department of Shalya – Shalakya, Faculty of Indigenous Medicine, Gampaha Wickramarachchi University of Indigenous Medicine, Yakkala, Sri Lanka
Fahara Meedin Senior Staff Technical Officer, Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Sri Lanka
Samantha Bandara Ph.D. Student Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University Level 2, Ralph, and Patricia Sarich Neuroscience Research Institute (SNRI)8 Verdun St, Nedlands Western Australia

DOI:

https://doi.org/10.29121/jahim.v3.i1.2023.26

Keywords:

Oral Health, Poly Herbal Formulation, Plant Extract

Abstract [English]

Introduction: Natural medicines prescribed by the traditional Ayurvedic medical system of Sri Lanka have been extensively used to treat and prevent oral diseases.
Objective: Here, we investigated the antimicrobial effect of Ayurveda polyherbal formulation, mentioned in authentic text as Gandusha (mouth wash) consisting of Jasminum officinale leaves, Terminalia chebula fruits, Tinospora cordifolia stem, Desmodium triflorum whole plant and Glycyrrhiza glabra roots.
Methods: Anti-microbial susceptibility of the poly herbal preparation against common oral pathogens (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Enterococcus faecalis) was tested using agar well diffusion method. Minimum inhibitory (MIC) was expressed in mg of freeze-dried extract per millilitres of agar solution.
Results: The plant extract has considerable antimicrobial activity against Staphylococcus aureus and Enterococcus faecalis. The lowest MIC of 250mg/ml was shown against Enterococcus faecalis and Staphylococcus aureus.
Conclusions: The polyherbal formulation is effective in mitigating the bacterial growth and hence enhance the oral health protection.

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