International Journal of Engineering Science Technologies https://granthaalayahpublication.org/ojs-sys/ijoest <p>International Journal of Engineering Science Technologies is an open access peer reviewed journal that provides bi-monthly publication of articles in all areas of Engineering, Technologies and Science. It is an international refereed e-journal. IJOEST have the aim to propagate innovative research and eminence in knowledge. IJOEST Journals has become a prominent contributor for the research communities and societies. IJOEST Journal is making the bridge between research and developments.</p> <p>Editor-in-chief:<br />Dr. Pratosh Bansal (Professor, Department of Information Technology, Institute of Engineering &amp; Technology, Devi Ahilya Vishwavidyalaya, India)</p> <p>Managing Editor:<br />Dr. Tina Porwal (PhD, Maharani Laxmibai Girls P.G. College, Indore, India)</p> Granthaalayah Publications and Printers en-US International Journal of Engineering Science Technologies 2456-8651 ENGINEERING APPROACHES IN THE DIAGNOSIS OF SLEEP APNEA https://granthaalayahpublication.org/ojs-sys/ijoest/article/view/743 <p>Sleep apnea is a sleep disorder that significantly affects human life and occurs as a result of repeated obstructions in the respiratory system lasting at least 10 seconds during sleep. The most common type, Obstructive Sleep Apnea (OSA), affects the upper respiratory tract, whereas Central Sleep Apnea (CSA) occurs due to dysfunction in the respiratory control center in the brain. Sleep apnea manifests with symptoms such as fatigue upon awakening, snoring, and daytime sleepiness. If left untreated, it may lead to serious health complications including stroke, cardiovascular diseases, and hypertension. Polysomnography (PSG) is the most widely used diagnostic method for sleep apnea. However, this test involves several limitations in terms of time consumption, patient comfort, and financial cost. Therefore, there is an increasing need for alternative engineering-based diagnostic support methods to complement polysomnography. Recent advancements in Biomedical Engineering, Electrical and Electronics Engineering, and Software Engineering have enabled the development of portable, cost-effective, and highly compatible systems for sleep apnea detection. Sleep apnea can be identified through the processing of physiological signals such as electroencephalography (EEG), electrocardiography (ECG), electrooculography (EOG), and oxygen saturation levels. The acquired data are analyzed using artificial intelligence techniques and machine learning algorithms, which have become prominent tools in biomedical signal analysis. Furthermore, the integration of wearable devices and Internet of Things (IoT)-based technologies allows continuous monitoring of patients in home environments. This study discusses the significance of engineering-based solutions in sleep apnea diagnosis and highlights their contributions to modern healthcare technologies.</p> Hatice Bilgili Elif Kucuktag Copyright (c) 2026 Hatice Bilgili, Elif Kucuktag https://creativecommons.org/licenses/by/4.0 2026-03-09 2026-03-09 10 2 1 12 10.29121/ijoest.v10.i2.2026.743 MAGNETIC DRUG TARGETING USING MAGNETIC NANOPARTICLES FOR CANCER THERAPY https://granthaalayahpublication.org/ojs-sys/ijoest/article/view/746 <p>Globally, cancer is still among the most frequent causes of mortality.Traditional cancer treatment modalities, including surgery, radiotherapy, and chemotherapy, present limited selectivity and severe side effects. Chemotherapeutic agents target the growth and survival of rapidly dividing cancer cells, but they can also kill healthy cells through systemic circulation. Hence, the quest for specific drug-targeting systems for tumor-targeting agents in the therapeutic arm has attracted considerable attention in cancer therapy. Magnetic nanoparticles (MNPs) have attracted significant attention in biomedical research owing to their specific physical and features such as their small particle size and high surface-to-volume, and superparamagnetic behavior. Magnetite (Fe₃O₄) and maghemite (γ-Fe₂O₃), which belong to the iron oxide nanoparticle family, are extensively investigated for biomedical because they are biocompatible and exhibit controllable magnetic properties. These nanoparticles can be functionalized with biocompatible coatings and anticancer agents to develop magnetic drug delivery systems. Magnetic Drug Targeting (MDT) is reliesed on the principle of magnetic nanoparticles conjugated with therapeutic agents directed to the cancerous tissue region by a magnetic field applied externall Such an approach makes increased drug accumulation within the targeted tissue possible, and a substantial impact has been achieved with systemic toxicity and side effects minimized. Furthermore, magnetic nanoparticles have been applied widely across biomedical fields, including magnetic resonance imaging (MRI), hyperthermia therapy, biosensors, and tissue engineering. The basic properties of magnetic nanoparticles, their biocompatibility, their application in cancer anticancer drug targeting using magnetic drug, and their properties in the context of the basic characteristics are investigated in this review as well. In addition, discussion has been provided on magnetic targeting dynamics, drug applications, and anti-cancer drugs with magnetic nanoparticles, as well as targeted drug system issues, based on the available literature. Drug delivery using magnetic nanoparticle systems is a promising strategy for optimizing cancer treatment while minimizing side effects.</p> Hatice Bilgili Copyright (c) 2026 Hatice Bilgili https://creativecommons.org/licenses/by/4.0 2026-03-12 2026-03-12 10 2 13 29 10.29121/ijoest.v10.i2.2026.746